The aim of the present study was to assess the outcome of lung cancer patients who were admitted to a medical intensive care unit (MICU) and to identify the measurable predictors of their MICU outcome. In each of three randomised phase-III studies, a treatment interaction effect with histology has been identified . Four different collaborative research groups attempted to construct prognostic classifications making use only of independent prognostic factors . Further consensus about the adequate methodology to search and identify new prognostic factors is lacking; indeed, we have no agreement on the set of factors that should systematically be used to adjust the effect of new factors and how to assess what independent additional value a new factor brings. A retrospective analysis of the IALT trial suggests that p27 negative characteristic may also be a predictive factor of benefit from cisplatin-based adjuvant chemotherapy . Limited stage small cell lung cancers have a much better prognosis than extensive stage cancers. Further studies, either subgroups analyses of the first randomised trials or randomised trials having used of an enrichment design (i.e. Early stages of lung cancer have a better prognosis than later stages. Median survival times in months were the following: IA: 26; IB: 21; IIA: 15; IIB: 12; IIIA: 13; IIIB: 11; and IV: 6. People who are in better overall health are more likely to be able to have surgery to remove the lung cancer, which may improve survival. Other negative prognostic factors included increased age and men for the LD‐SCLC group and increased age, men, increased number of metastatic sites at baseline, … Early stages of lung cancer (stages 0 and 1) have a better prognosis than later stages (stages 2, 3 or 4). The Role of Prognostic Factors and Oncogenes in the Detection and Management of Non-Small-Cell Lung Cancer. 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